Deep Trouble #8 – Tim Errington
with Dr Mark Halloran
Or listen on iTunes, Spotify or Stitcher
In this episode we are in conversation with biologist Dr Tim Errington, Director of Metascience for the Center for Open Science (COS), which is dedicated to the replication of scientific research. First we discuss the Reproducibility Project: Psychology, which found that of the 97% of significant results published in high-ranking psychological science journals only 36% of the replications were significant. We discuss some of the post-hoc explanations provided by researchers to explain this failure of replication, as well as the funding incentive system within science which discourages reproduction of research. We follow on from this by discussing the Reproducibility Project: Cancer Biology, which aimed to reproduce medical studies that were published in top-tier journals such as Nature, Science and Cell. So far, 3 of the 5 studies they have attempted to reproduce had strikingly different results from the originals. We discuss this in terms of the extremely high failure rate of phase 2 clinical trials, and how these drugs may not make it into human trials if the pre-clinical trials were more statistically and methodologically robust. We also talk about the general statistical illiteracy in the field as well as the extreme pressure to find positive results in science which is dominated by a culture of ‘publish or perish’.
Like what you hear? Listen to all of the Deep Trouble interviews we’ve run to date.
Sponsored by
Making Trouble : John Waters
October 6, 2019 | troublemag
interview by Dr Mark Halloran
Q. I was interested in your childhood, and your parents Patricia and John, and being raised as a Roman Catholic in Baltimore. I was raised a Roman Catholic as well so I feel as though … Read More
The Road to Darwin
October 5, 2019 | troublemag
part one
Ben Laycock
Chapter 1 – Hattah
We leave Castlemaine on the last day of July, heading for Darwin and beyond. We don’t see anything to write home about on the first day. Inglewood seems like a thriving little … Read More
Our Bodies, Our Voices, Our Marks
August 8, 2019 | troublemag
Immigration Museum
until 6 October 2019
A suite of exhibitions and experiences exploring the art of tattoo, alongside themes of identity, self-expression, culture and community.
In order of appearance:
SEPTEMBER/OCTOBER 2019 COVER: From Paul Stillen’s Connected Bodies, Vess 2019. Photograph … Read More
The David Roche Legacy
August 1, 2019 | troublemag
by Inga Walton
On an unassuming street in North Adelaide can be found one of Australia’s more recent, and arguably most lavish, house museums. The David Roche Foundation is the first private museum in Adelaide established without public funding, and … Read More
The Fashion Force
July 2, 2019 | troublemag
by Inga Walton
Krystyna Campbell-Pretty’s passion for fashion has endowed the National Gallery of Victoria with a substantial number of exceptional couture and prêt-à-porter ensembles, accessories, sketches and studio drawings, photography, fashion journals and supporting textual material over the last … Read More
Deep Trouble’s War on The Chaser’s War on the 2019 Election Result
June 9, 2019 | troublemag
In this SPECIAL EPISODE of Deep Trouble we interview Charles Firth of the Chaser. He offers an analysis of the state of play for the major parties in 2019, why the Labour Party lost the ‘unlosable’ election, as well as … Read More
Bob’s Convoy
June 6, 2019 | troublemag
by Ben Laycock
PART ONE : The Long Road to the Far North
We set off from Castlemaine on a glorious afternoon: three enthusiastic, intrepid activists on a journey into the heart of darkness. We are not alone. Bob … Read More
IVE
June 6, 2019 | troublemag
Ive Sorocuk – Comics Face Supreme
Trouble met Ive Sorocuk at the same comic con called Supanova in 2008 where they met Mandy Ord. We were immediately attracted to his weird sense of humour, his superheroes, The Diggables, and … Read More
SALON April-May 2019
April 27, 2019 | troublemag
APRIL/MAY 2019 COVER: Richard NGUYEN, All mixed up (detail) 2018, digital video, duration 1:57 min. Canning Vale College. Pulse Perspectives, Art Gallery of Western Australia, Perth Cultural Centre, Perth (WA), 6 April – 22 July 2019 – artgallery.wa.gov.au
Yvette COPPERSMITH, … Read More
Getting Personal with Vince Jones
April 27, 2019 | troublemag
interview by Steve Proposch
Vince Jones remembers playing in the Wollongong under 10s soccer team. “I was born in Paisley, just outside of Glasgow. My dad ran out of steam for Scotland at the time. He wanted to go somewhere … Read More
-
Dressing the Movies Part One by Inga Walton
75436 Views
