Deep Trouble #8 – Tim Errington
with Dr Mark Halloran
Or listen on iTunes, Spotify or Stitcher
In this episode we are in conversation with biologist Dr Tim Errington, Director of Metascience for the Center for Open Science (COS), which is dedicated to the replication of scientific research. First we discuss the Reproducibility Project: Psychology, which found that of the 97% of significant results published in high-ranking psychological science journals only 36% of the replications were significant. We discuss some of the post-hoc explanations provided by researchers to explain this failure of replication, as well as the funding incentive system within science which discourages reproduction of research. We follow on from this by discussing the Reproducibility Project: Cancer Biology, which aimed to reproduce medical studies that were published in top-tier journals such as Nature, Science and Cell. So far, 3 of the 5 studies they have attempted to reproduce had strikingly different results from the originals. We discuss this in terms of the extremely high failure rate of phase 2 clinical trials, and how these drugs may not make it into human trials if the pre-clinical trials were more statistically and methodologically robust. We also talk about the general statistical illiteracy in the field as well as the extreme pressure to find positive results in science which is dominated by a culture of ‘publish or perish’.
Like what you hear? Listen to all of the Deep Trouble interviews we’ve run to date.
Sponsored by
Merran Esson : Standing Still and Silently Balancing
June 7, 2020 | troublemag
The Western Sydney University Sculpture Award & Exhibition has been postponed until 2021 due to COVID-19, but the finalists have been announced. Congratulations to: Mark Booth, Jennifer Cochrane, Chris Edwards, Harrie Fasher, John Fitzmaurice, Jim Flook, Martin George, Akira Kamada, … Read More
Hey COVID-19 Thanks for the Good Times
June 1, 2020 | troublemag
Callum R. Scott
One afternoon you rock up to your hospo job with a hangover, only to find that it’s closed its doors indefinitely and suddenly you’re unemployed again. With fuck all in your savings account, you decide to drown … Read More
Head On Photo Festival
April 7, 2020 | troublemag
1 – 17 May 2020
This year the festival will stage an online version of the event, accompanied by a program of online seminars and events throughout the Festival period. The festival will then work to present a scaled-back physical … Read More
Dear Tree
April 7, 2020 | troublemag
a listening experience created by Rose Turtle Ertler
“Dear tree,
Thank you for being here today for me and for everyone,
casting shade and giving a fresh breath
with deep and bold colours and gentle stillness.”
– by a contributor … Read More
Love in a Time of Coronavirus
April 7, 2020 | troublemag
by Callum R Scott
And just as the zombie apocalypse kicked in, I quit my job. I’ll tell you why later in the piece. So, now I find myself unemployed at 50, in the middle of a pandemic. This is … Read More
Synthetica : art, technology & us
February 12, 2020 | troublemag
Dr Cameron Rose
Art and technology are by definition divorced from nature. Art is the product of human creativity and technique; it is an object, image, sound or movement that exists as a unique manifestation of our imagination. Technology comes … Read More
CAN’T DO TOMORROW
February 11, 2020 | troublemag
Australia’s largest showcase of urban & street art
20 – 29 February 2020
This inaugural festival will see over 100 street artists and musicians take over Melbourne’s iconic multi-level warehouse, The Facility, transforming it from top to bottom with paintings, … Read More
The Road to Darwin
December 14, 2019 | troublemag
Chapter 4 – The Alice
Rolled into Alice Springs, literally: a strong head wind burnt up all the petrol. As the sun set in the west (I presume it was the west because that’s where the sun sets where I … Read More
Terminus : Jess Johnson & Simon Ward
December 8, 2019 | troublemag
Heide Museum of Modern Art presents
a mysterious universe of alien architecture populated by humanoid clones and cryptic symbols, explored via a network of travellators and gateways.
2 November 2019 – 1 March 2020
IMAGE CREDITS: … Read More
Arthur Boyd : Landscape of the Soul
December 6, 2019 | troublemag
by Alexandra Sasse
Have you had any lessons? The enquiry came from a woman and her friend who had been loitering behind me as I painted en plein air in a local park. It seemed a particularly stupid question, especially … Read More
-
Dressing the Movies Part One by Inga Walton
76547 Views
