Deep Trouble #8 – Tim Errington
with Dr Mark Halloran
Or listen on iTunes, Spotify or Stitcher
In this episode we are in conversation with biologist Dr Tim Errington, Director of Metascience for the Center for Open Science (COS), which is dedicated to the replication of scientific research. First we discuss the Reproducibility Project: Psychology, which found that of the 97% of significant results published in high-ranking psychological science journals only 36% of the replications were significant. We discuss some of the post-hoc explanations provided by researchers to explain this failure of replication, as well as the funding incentive system within science which discourages reproduction of research. We follow on from this by discussing the Reproducibility Project: Cancer Biology, which aimed to reproduce medical studies that were published in top-tier journals such as Nature, Science and Cell. So far, 3 of the 5 studies they have attempted to reproduce had strikingly different results from the originals. We discuss this in terms of the extremely high failure rate of phase 2 clinical trials, and how these drugs may not make it into human trials if the pre-clinical trials were more statistically and methodologically robust. We also talk about the general statistical illiteracy in the field as well as the extreme pressure to find positive results in science which is dominated by a culture of ‘publish or perish’.
Like what you hear? Listen to all of the Deep Trouble interviews we’ve run to date.
Sponsored by
CAN’T DO TOMORROW
February 16, 2020 | troublemag
Australia’s largest showcase of urban & street art
20 – 29 February 2020
This inaugural festival will see over 100 street artists and musicians take over Melbourne’s iconic multi-level warehouse, The Facility, transforming it from top to bottom with paintings, … Read More
Synthetica : art, technology & us
February 16, 2020 | troublemag
Dr Cameron Rose
Art and technology are by definition divorced from nature. Art is the product of human creativity and technique; it is an object, image, sound or movement that exists as a unique manifestation of our imagination. Technology comes … Read More
The Road to Darwin
December 14, 2019 | troublemag
Chapter 4 – The Alice
Rolled into Alice Springs, literally: a strong head wind burnt up all the petrol. As the sun set in the west (I presume it was the west because that’s where the sun sets where I … Read More
Terminus : Jess Johnson & Simon Ward
December 8, 2019 | troublemag
Heide Museum of Modern Art presents
a mysterious universe of alien architecture populated by humanoid clones and cryptic symbols, explored via a network of travellators and gateways.
2 November 2019 – 1 March 2020
IMAGE CREDITS: … Read More
Arthur Boyd : Landscape of the Soul
December 5, 2019 | troublemag
by Alexandra Sasse
Have you had any lessons? The enquiry came from a woman and her friend who had been loitering behind me as I painted en plein air in a local park. It seemed a particularly stupid question, especially … Read More
Making Trouble : John Waters
October 6, 2019 | troublemag
interview by Dr Mark Halloran
Q. I was interested in your childhood, and your parents Patricia and John, and being raised as a Roman Catholic in Baltimore. I was raised a Roman Catholic as well so I feel as though … Read More
The Road to Darwin
October 5, 2019 | troublemag
part one
Ben Laycock
Chapter 1 – Hattah
We leave Castlemaine on the last day of July, heading for Darwin and beyond. We don’t see anything to write home about on the first day. Inglewood seems like a thriving little … Read More
Our Bodies, Our Voices, Our Marks
August 8, 2019 | troublemag
Immigration Museum
until 6 October 2019
A suite of exhibitions and experiences exploring the art of tattoo, alongside themes of identity, self-expression, culture and community.
In order of appearance:
SEPTEMBER/OCTOBER 2019 COVER: From Paul Stillen’s Connected Bodies, Vess 2019. Photograph … Read More
The David Roche Legacy
August 1, 2019 | troublemag
by Inga Walton
On an unassuming street in North Adelaide can be found one of Australia’s more recent, and arguably most lavish, house museums. The David Roche Foundation is the first private museum in Adelaide established without public funding, and … Read More
The Fashion Force
July 2, 2019 | troublemag
by Inga Walton
Krystyna Campbell-Pretty’s passion for fashion has endowed the National Gallery of Victoria with a substantial number of exceptional couture and prêt-à-porter ensembles, accessories, sketches and studio drawings, photography, fashion journals and supporting textual material over the last … Read More
-
Dressing the Movies Part One by Inga Walton
75659 Views
